Page 14 - Mouse Molecular Genetics

Plenary/Platform Sessions
14
Wednesday, October 3 2:00 pm–3:00 pm
Merrill Hall
Beddington Lecture
18
- 2:00
Hox genes and hindbrain patterning: A story in
segments. Robb Krumlauf
1,2
,
Youngwook Ahn
1
,
Christof Nolte
1
,
Hugo Parker
1
,
Marina Yurieva
1
,
Bony
DeKumar
1
. 1)
Stowers Institute, Kansas City, MO; 2)
Department of Anatomy and Cell Biology, Kansas
University Medical School, Kansas City, KS.
Wednesday, October 3 7:00 pm–10:40 pm
Merrill Hall
Plenary/Platform Session 3 - Stem
Cells and Germ Cells
Chair: Frederic de Sauvage, Genentech, Inc.
19
- 7:00
Targeting developmental pathways in cancer cells and
stem cells. Frederic J. de Sauvage
.
Genentech Inc., So.
San Francisco, CA.
20
- 7:30
Lineage analysis of basal epithelial cells reveals their
unexpected plasticity and supports a cell of origin
model for prostate cancer heterogeneity. Zhu Wang
1,4
,
Antonina Mitrofanova
2,4
,
Sarah Bergren
1,4
,
Cory Abate-
Shen
3,4
,
Andrea Califano
2,4
,
Michael Shen
1,4
. 1)
Depts of
Medicine and Genetics and Development, Columbia U
Med Center, New York; 2) Department of Biomedical
Informatics and Center for Computational Biology and
Bioinformatics, Columbia University Medical Center,
New York, NY; 3) Departments of Urology and
Pathology and Cell Biology, Columbia University
Medical Center, New York, NY; 4) Herbert Irving
Comprehensive Cancer Ctr, Columbia U Med Ctr, NY.
21
- 7:50
Wnt/beta-catenin, BMP and HGF in cancer stem
cells. Walter Birchmeier
1
,
Peter Wend
1,2
,
Ulrike
Ziebold
1
,
Jane Holland
1
. 1)
Max-Delbrueck-Center for
Molecular Medicine (MDC), 13125 Berlin, Germany; 2)
David Geffen School of Medicine, UCLA.
22
- 8:10
Discovery of a novel, developmentally restricted
hematopoietic stem cell.
Anna Beaudin, Scott
Boyer,
Camilla Forsberg
.
Inst for the Biology of Stem
Cells, Dept of Biomolecular Engineering, University of
California Santa Cruz.
23
- 8:30
A defensive role of Sirt3 against oxidative stress and
aging in preimplantation embryos. Yumiko
Kawamura
1,2,3
,
Yasunobu Uchijima
1
,
Koichi Nishiyama
1
,
Yukiko Kurihara
1
,
Kiyoshi Kita
2
,
Hiroki Kurihara
1
. 1)
Dept. of Phys. Chem. and Meta., Grad. Sch. of Med., the
Univ. of Tokyo, Tokyo, Japan; 2) Dept. of Biom. Chem.,
Grad. Sch. of Med., the Univ. of Tokyo, Tokyo, Japan; 3)
JSPS Research Fellow.
8:50
pm -
Break
24
- 9:10
The mouse Y-encoded transcription factor ZFY
promotes the second meiotic division and is essential
for sperm tail development and head
remodelling Nadege Vernet
,
Fanny Decarpentrie,
Shantha Mahadevaiah, Paul Burgoyne. Stem cell biology
and developmental genetics, NIMR, Medical Research
Council, UK, London.
25
- 9:30
FGFR2IIIc Is Required for Testis Determination but
Is Dispensable for Subsequent Testis Cord
Differentiation and Spermatogenesis.
Stefan Bagheri-
Fam
1
,
Meiyun Yong
1
,
Anja Dietrich
1
,
Terje Svingen
2
,
Peter Koopman
2
,
Veraragavan Eswarakumar
3
,
Vincent R.
Harley
1
. 1)
Molecular Genetics & Development, Prince
Henry's Inst, Clayton, VIC, Australia; 2) Institute for
Molecular Bioscience, University of Queensland, QLD,
Australia; 3) School of Medicine, Yale.
26
- 9:50
System-level analysis of sperm maturation in the
epididymis. Timothy Karr
1
,
Sheri Skerget
1
,
Konstantino
Petritis
2
,
Ashoka Polpitiya
2
. 1)
Biodesign Inst, Arizona
State Univ, Tempe, AZ; 2) Center for Proteomics,
Translational Genomics Research Institute, Phoenix, AZ.
27
- 10:10
Sonic hedgehog-expressing basal stem cells are the
cell-of-origin for bladder cancer. Philip A. Beachy
,
Kunyoo Shin, Agnes Lim, Sally Kawano. Stanford Univ
Sch Medicine, Stanford, CA.