Page 16 - Mouse Molecular Genetics

Plenary/Platform Sessions
16
Thursday, October 4 8:30 am–12:00 noon
Merrill Hall
Plenary/Platform Session 4 -
Epigenetics
Chair: Guo-Liang Xu, Institute of Biochemistry and Cell
Biology, Chinese Academy of Sciences
28
- 8:30
DNA Oxidation towards Totipotency in Mammalian
Development. Guo-Liang Xu
.
Institute of Biochemistry
and Cell Biology, Chinese Academy of Sciences,
Shanghai, China.
29
- 9:00
DNA dioxygenases regulate cardiac progenitor pool
and their differentiation in heart development. Qing-
Yan Cui
1
,
Guo-Liang Xu
1
,
Bin Zhou
2
. 1)
Group of DNA
Metabolism, The State Key Laboratory of Molecular
Biology, Institute of Biochemistry and Cell Biology,
Shanghai Institutes for Biological Sciences, Chinese
Academy of Sciences, Shanghai 200031, China; 2) Key
laboratory of Nutrition and Metabolism, Institute for
Nutritional Sciences, Shanghai Institutes for Biological
Sciences, Chinese Academy of Sciences, Graduate School
of the Chinese Academy of Sciences, Shanghai 200031,
China.
30
- 9:20
Dissection of the molecular mechanism that regulates
activation of murine IAP (intracisternal A particles)
retrotransposons upon DNA demethylation in ES
cells.
Jafar Sharif
1
,
Takaho A. Endo
2
,
Kayoko
Katsuyama
1
,
Yoko Mizutani-Koseki
1
,
Yoko Kuroki
1
,
Tomoyuki Ishikura
1
,
Takanori Hasegawa
1
,
Osamu
Ohara
1
,
Tetsuro Toyoda
2
,
Yoichi Shinkai
3
,
Haruhiko
Koseki
1
. 1)
RIKEN Center for Allergy & Immunology
(
RCAI), Japan; 2) RIKEN Bioinformatics and Systems
Engineering Division (BASE), Japan; 3) RIKEN
Advanced Science Institute (ASI), Japan.
31
- 9:40
Alterations in genomically imprinted noncoding RNA
clusters in a mouse model of Fetal Alcohol Spectrum
Disorders (FASD). Benjamin Laufer
,
Janus Katherine,
Kleiber Morgan, Eric Diehl, Sean Addison, Shiva Singh.
Biology, Western University, London, Ontario, Canada.
10:00
am -
Break
32
- 10:20
MeCP2 Interacting Partners in Development and Rett
Syndrome. Mary Donohoe
1,2,3
,
Siva Muthuswamy
1,2,3
,
Tao Wu
1,2,3
. 1)
Burke Medical Research Institute, White
Plains, NY; 2) Dept of Neuroscience Weill Cornell
Medical College New York, NY; 3) Dept of Cell and
Developmental Biology Weill Cornell Medical College
New York, NY.
33
- 10:40
The histone H2B ubiquitin ligase Rnf20 is required for
self-renewal and pluripotency in mouse ES cells. Kit
Wan Ma
,
Takaho A. Endo, Jafar Sharif, Haruhiko
Koseki. RCAI, RIKEN Yokohama Institute, Yokohama,
Kanagawa, Japan.
34
- 11:00
Upregulation of the mammalian X chromosome is
associated with enhanced transcription initiation and
epigenetic modifications. Xinxian Deng
1
,
Joel Berletch
1
,
Joseph Hiatt
2
,
Di Kim Nguyen
1
,
Jay Shendure
2
,
Christine
Disteche
1,3
. 1)
Dept Pathology, Univ Washington, Seattle,
WA; 2) Dept Genome Sciences, Univ Washington,
Seattle, WA; 3) Dept Medicine, Univ Washington,
Seattle, WA.
35
- 11:20
Nuclear transfer for the study of X chromosome
inactivation in mice. Atsuo Ogura
1,2
,
Shogo Matoba
1
,
Mami Oikawa
1,3
,
Kimiko Inoue
1,2
,
Fumitoshi Ishino
3
. 1)
BioResource Center, RIKEN, Tsukuba, Ibaraki, Japan; 2)
Graduate School of Life and Environmental Science,
University of Tsukuba, Ibaraki, Japan; 3) Department of
Epigenetics, Medical Research Institute, Tokyo Medical
and Dental University, Tokyo, Japan.