Page 18 - Mouse Molecular Genetics

Plenary/Platform Sessions
18
Thursday, October 4 2:00 pm–3:00 pm
Merrill Hall
Keynote Address
36
- 2:00
Development of Hematopoietic Stem Cell: A final
scenario. Shinichi Nishikawa
.
Riken Center for
Developmental Biology, Kobe, Kobe, Japan.
Thursday, October 4 7:00 pm–10:20 pm
Merrill Hall
Plenary/Platform Session 5 -
Technology
Chair: Anton Wutz, Wellcome Trust Centre for Stem Cell
Research
37
- 7:00
Characterization of haploid embryonic stem cells from
mouse embryos. Anton Wutz
,
Martin Leeb. Wellcome
Trust Centre for Stem Cell Research, Cambridge,
Cambridgeshire, United Kingdom.
38
- 7:30
MFA: A Novel Method For The Generation Of “All-
In-One” Null And Conditional Alleles.
Christopher
Schoenherr, Evangelos Pefanis, Peter Lengyel, Darshi
Persaud, YuHong Zhang, Ronald Deckelbaum, Julie
Kalter, Dimitrios Skokos, Peter Yang, Andrew J.
Murphy,
Aris N. Economides
.
Regeneron
Pharmaceuticals, Tarrytown, NY.
39
- 7:50
Efficient generation of a conditional knock-out allele
in mice by zinc finger nuclease-mediated gene
targeting.
Keith Anderson
1
,
Jeremy Burton
1
,
Tuija
Alcantar
2
,
Jinjie Li
2
,
Robert Schwingendorf
2
,
Tim
Soukup
1
,
Merone Roose-Girma
1
,
J. Colin Cox
2
,
Xin
Rairdan
2
,
Weilan Ye
1
,
Soren Warming
1
. 1)
Department
of Molecular Biology, Genentech, Inc., 1 DNA Way,
South San Francisco, CA 94080; 2) Department of Mouse
Genetics, Genentech, Inc., 1 DNA Way, South San
Francisco, CA 94080.
40
- 8:10
Next generation RNAi mouse models for drug
discovery and toxicology assessment. Prem
Premsrirut
1
,
Christof Fellmann
1
,
Lukas Dow
2
,
Johannes
Zuber
3
,
Gregory Hannon
4
,
Scott Lowe
2
. 1)
Research &
Development, Mirimus Inc., Cold Spring Harbor, NY; 2)
Cancer Biology, Memorial Sloan Kettering Cancer
Center, New York, NY; 3) Differentiation and Disease,
Institute of Molecular Pathology, Vienna, Austria; 4)
Bioinformatics and Genomics, Cold Spring Harbor
Laboratory, Cold Spring Harbor, NY.
8:30
pm -
Break
41
- 8:50
Constructing functional genetic networks in
mammalian cells. Christopher Kemp
,
Russell Moser,
Michael Kao, Chang Xu, Carla Grandori, Eddie Mendez.
Fred Hutchinson Cancer Research Center, Seattle, WA.
42
- 9:10
Hot or Not?: Leveraging mouse genome diversity to
identify hotspots of copy number variants. Kathleen
A. Hill
1
,
M. Elizabeth O. Locke
2
,
Andrea E. Wishart
3
,
Susan T. Eitutis
3
,
Jenna Butler
2
,
Mark Daley
1
. 1)
Department of Biology and Computer Science, The
University of Western Ontario, London, ON, Canada; 2)
Department of Computer Science, The University of
Western Ontario, London, ON, Canada; 3) Department of
Biology, The University of Western Ontario, London,
ON, Canada.
43
- 9:30
PRISM.stanford.edu: 2,500 Human and Mouse
transcription factor developmental function
predictions.
Aaron Wenger
1
,
Shoa Clarke
2
,
Jenny Chen
3
,
Cory McLean
1
,
Gill Bejerano
1,4
. 1)
Computer Science,
Stanford Univ, Stanford, CA; 2) Genetics, Stanford Univ,
Stanford, CA; 3) Biomedical Informatics, Stanford Univ,
Stanford, CA; 4) Developmental Biology, Stanford Univ,
Stanford, CA.
44
- 9:50
Generation of rat-mouse interspecific chimeras for
study of organogenesis and elucidation of xenogenic
barrier. Hiromitsu Nakauchi
1,2
. 1)
Division of Stem
Cell Therapy, Center for Stem Cell Biology and
Regeneration Medicine, Institute of Medical Science,
University of Tokyo, Japan; 2) Japan Science Technology
Agency, ERATO, Nakauchi Stem Cell and Organ
Regeneration Project.